Data Integrity issues are like Diabetes it is not hard to controlled diabetes by better life style (Data Integrity Issues by Better Compliance and Automation &CSV). If diabetes is not controlled well it can be source of many diseases and has the power to kill the person when combined with other disease attack. Now as full GMP 21 CFR part 211 and 201 slowly coming to computers Data Integrity issue has become like Diabetes. If not controlled it can harm ever where and it can be dangerous for Financial health of any company. We have seen 1/3rd or 1/4th of market cap erosion of many companies last two years after getting 483 or warning letter.